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PRODID:-//Virginia Tech//VT Calendar//EN
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DTSTAMP:20130508T160000Z
UID:1367607099076@events.msu.edu
CATEGORIES:Conferences / Seminars / Lectures
DTSTART:20130508T160000Z
DTEND:20130508T170000Z
SUMMARY:MICHAEL WANG, MD/PhD - Associate Professor of Neurology,  U of M, Ann Arbor, MI
DESCRIPTION:
 BRAIN ARTERIOPATHY IN INHERITED SMALL VESSEL DISEASE\n
 \n
 HOST: 
   Anne Dorrance\n
 \n
 Small vessel 
 disease (SVD) of the brain occurs in up to 
 half of the population by the age of 65.  Emerging 
 evidence supports SVD as an important 
 risk factor in the development of stroke, dementia, 
 and Parkinson's disease.  Unfortunately, 
 the mechanisms behind this neurological risk 
 factor remain obscure, and there are no treatments 
 for SVD.  Our studies focus on the inherited 
 disorder CADASIL, which results in early 
 onset and severe SVD.  CADASIL is caused 
 by mutations in NOTCH3.  We will describe investigations 
 that have revealed new clearance 
 pathways for the NOTCH3 protein and novel NOTCH3 
 binding proteins.  Elucidation of molecules 
 governing NOTCH3 biology may reveal possible 
 treatment strategies and uncover core pathways 
 that lead to SVD.\n
 \n\n
 Price: free\n
 Sponsor: Administration\n
 Sponsor's Homepage: http://phmtox.msu.edu/events/pdf/WANG%20M--Flyer.pdf\n
 Contact name: Diane Hummel\n
 Contact phone: 884-3553\n
 Contact email: phm@msu.edu\n
 for more info visit the web at:\n 
 http://phmtox.msu.edu/events/pdf/WANG%20M--Flyer.pdf\n
LOCATION:B448-449 Life Sciences
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