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DTSTAMP:20150216T170000Z
UID:1423680578274@events.msu.edu
CATEGORIES:Conferences / Seminars / Lectures
DTSTART:20150216T170000Z
DTEND:20150216T180000Z
SUMMARY:Corey R. Hopkins, Ph.D.
DESCRIPTION:
 Research Assistant Professor\n
 Vanderbilt Center 
 for Neuroscience Drug Discovery\n
 \n
 Discovery 
 and Development of Small Molecules As Potential 
 First-In-Class Therapeutics\n
 \n
 HOST: Richard 
 Neubig, M.D., Ph. D.\n
 \n
 The seminar will 
 highlight work from my laboratory in the discovery 
 and development of novel tool compounds 
 for a variety of therapeutic indications. Work 
 covered will include positive allosteric 
 modulators (PAMs) of the metabotropic glutamate 
 receptor 4 for Parkinson's disease, novel 
 BMP inhibitors/potentiators for Tylenol overdose 
 and fibrodysplasia ossificans progressiva 
 (FOP) and inhibitors of TRPC4/5 for the protection 
 of the kidney filter. Compounds were identified 
 by traditional high-throughput screening 
 as well as from a high-content in vivo 
 zebrafish screen and optimized utilizing iterative 
 medicinal chemistry, in vitro and in vivo 
 PK, and in vivo animal models at Vanderbilt 
 University.\n\n
 Price: Free\n
 Sponsor: Dept of Pharmacology & Toxicology\n
 Sponsor's Homepage: http://phmtox.msu.edu/\n
 Contact name: Student Office\n
 Contact phone: (517) 884-0409\n
 Contact email: phm@msu.edu\n
 for more info visit the web at:\n 
 http://phmtox.msu.edu/education/Seminars-PhmTox.htm\n
LOCATION:B448 Life Sciences  (behind Bott Nursing Building)
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