3rd ANNUAL THEODORE M. BRODY DISTINGUISHED LECTURE
(Conferences / Seminars / Lectures)
RAY DINGLEDINE, PhD more information...
Professor and Chair
Department of Pharmacology
Emory University School of Medicine Atlanta, GA
HIGH THROUGHPUT STRATEGIES FOR MODIFYING EPILEPSY
HOST: JOSEPH R. HAYWOOD
A major goal in neuropharmacology is to devise disease-modifying therapies for chronic neurological disorders such as epilepsy. We are using large-scale transcriptional profiling of neurons thought to be involved in the process of epileptogenesis to suggest novel pathways and protein targets. We then use high throughput screening for small molecule modulators of these targets to develop new reagents that can be used to probe specific receptors in epilepsy-related pathways. The successes and challenges of this approach in academic laboratories will be discussed.