Sex differences in the neural control of circulation are increasingly being recognized, yet underlying mechanisms remain equivocal. The sympathetic nervous system is central to the regulation of both short- and long-term blood pressure, and evidence is beginning to emerge indicating altered sympathetic neural activity (and reactivity) not only between men and women, but also within women at various stages of the ovarian cycle. This seminar will explore the influence of sex and the ovarian cycle on post-ganglionic sympathetic neural outflow in humans via the technique of microneurography. More specifically, Dr. Carter will compare sympathetic neural control and reactivity in 1) young men and women, and 2) premenopausal women during high and low levels of estradiol and progesterone. These findings will be discussed as they pertain to increased risk of orthostatic intolerance in young women, as well as the post-menopausal surge in cardiovascular disease.

Location:	1425 Biophysical Science Bldg [map]
Price:	free
Sponsor:	Administration
Contact:	Diane Hummel phm@msu.edu 884-3553
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