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Today is:
Tue, Oct 26, 2021


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12:00pm
to
1:00pm
Corey R. Hopkins, Ph.D.  (Conferences / Seminars / Lectures)

Research Assistant Professor
Vanderbilt Center for Neuroscience Drug Discovery

Discovery and Development of Small Molecules As Potential First-In-Class Therapeutics

HOST: Richard Neubig, M.D., Ph. D.

The seminar will highlight work from my laboratory in the discovery and development of novel tool compounds for a variety of therapeutic indications. Work covered will include positive allosteric modulators (PAMs) of the metabotropic glutamate receptor 4 for Parkinson's disease, novel BMP inhibitors/potentiators for Tylenol overdose and fibrodysplasia ossificans progressiva (FOP) and inhibitors of TRPC4/5 for the protection of the kidney filter. Compounds were identified by traditional high-throughput screening as well as from a high-content in vivo zebrafish screen and optimized utilizing iterative medicinal chemistry, in vitro and in vivo PK, and in vivo animal models at Vanderbilt University.

more information...


Location: B448 Life Sciences (behind Bott Nursing Building) [map]
Price: Free
Sponsor: Dept of Pharmacology & Toxicology
Contact: Student Office
email pic phm@msu.edu
phone pic (517) 884-0409